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Author Topic: Charles Kerchner announces Y-STR Mutation Rates Project  (Read 2876 times)
Terry Barton
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Posts: 1679

« on: January 14, 2005, 07:22:52 PM »

Charlie's posting to the Rootsweb Genealogy-DNA-L is reproduced here in its entirety.


From: Charles
Sent: Friday, January 14, 2005 4:53 PM
Subject: [DNA] New Genetic Genealogy Project and Study Announced - Surname Projects Y-STR Haplotype Average Mutation Rate Log and Study -- formal announcement


In an effort to have tools to promote the existence of my new Surname Projects Y-STR Haplotype Average Mutation Rate Log and this new genetic genealogy study project, I have drafted the following announcement and hypothesis statement. Comments welcome.

Charles F. Kerchner, Jr., P.E., developer of the MtDNA Test Results Log and the DNAPrint Test Results Log used over the past couple years to aide Genetic Genealogists, has launched a new data collection Log to gather data to study whether there are intrinsic underlying unknown causes of the differences observed between the Y-STR Haplotype Average Mutation Rates from one surname project (male line) to another surname project (male line).

Hypothesis: That the Y-STR markers in one male line's Y chromosome consistently mutate on average over time and over the generations at a different average rate than another male line's Y chromosome Y-STR average mutation rate? That is the hypothesis he will test. And is this hypothesis true for all male lines in general, i.e., does each male line Y chromosome have its own unique intrinsic Y-STR haplotype average mutation rate? Is the Y-STR marker average mutation rate male line specific? Some surname projects apparently have very low average mutation rates as evidenced by few mutations being reported by the Project Administrator, with their project participants having a known male common ancestor many, many generations back in time. Other surname projects apparently have markedly higher average mutation rates, two to three or even four times higher with even less generations to a common male ancestor than the project with the slower rate. The evidence has been anecdotal to date. Many comments on this observed phenomena have attributed the observed differences solely due to statistical aberrations. But as more and more surname project started, the anecdotal evidence has been building that something other than statistical aberrations is going on worth investigating.?

Charles believes there could be an underlying, here-to-date unknown mechanism in the in each Y chromosome line's copying/replicating mechanism and/or a repairing mechanism which differs from one male line to another male line, such that the net Y-STR Haplotype Average Mutation Rate can differ markedly from one male line to another, and thus from one surname project to another. And since the Y chromosome is inherited over time via the direct male line, it seems logical that any underlying suggested intrinsic mechanism affecting a specific male line average mutation rate would be inherited from father to son over the generations.

Charles, a retired professional engineer, hobby genealogist for almost 30 years, and a pioneering Genetic Genealogist for the last four years, will use the synergistic efforts of hundreds of Genetic Genealogists managing surname projects to compile the data for subsequent analysis, possibly even by a professional population geneticist or other scientist, to see if there is merit to his new male line specific mutation model and theory. Is it a one size mutation rate average fits all male lines for the Y-STR Haplotype Average Mutation Rate or is the average mutation rate male line specific? For more on his ideas on male line specific Y-STR haplotype average mutation rates, to view his new Log and read entries to date, see these webpages:

Webpage link to the announcement to be used to circulate the announcement to attract attention of surname project administrators and/or other interested websites or relevant publications:

Synergy at Work!

Charles F. Kerchner, Jr., P.E.
Genealogist and Genetic Genealogy Pioneer
« Last Edit: March 04, 2005, 08:27:45 PM by terry » Logged
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