World Families Forums - Question about chip-based SNP testing

ARCHIVAL COPY
Home Help Search Login Register
This is an archival copy of the old forum. This copy does not allow new posts, nor can you log in to this forum.
For the current active forum, please visit https://www.worldfamilies.net/forum.

+  World Families Forums
|-+  General Forums - Note: You must Be Logged In to post. Anyone can browse.
| |-+  General Discussion
| | |-+  Question about chip-based SNP testing
« previous next »
Pages: [1] Go Down Print
Author Topic: Question about chip-based SNP testing  (Read 1204 times)
wing_genealogist
Senior Member
***
Offline Offline

Posts: 82


WWW
« on: August 04, 2012, 08:28:32 AM »

Could some SNPs be placed on a chip which cannot be found via Sanger testing? Or is it necessary for there to be (basically the same) primers which are needed for Sanger testing to develop each individual probe for the chip?

I'm wondering (out loud) if there may end up some SNPs on the Nat Geno 2.0 chip which FT-DNA cannot make available (due to primer-related issues)
Logged

Y-DNA - R1b M157.2 (a private/family subclade of Z6/Z352) 111 markers tested

mt-DNA - J1c2g with the following private mutations: 315.1C 522.1A 522.2C C9974T C16256T (FMS tested and submitted to GenBank)

Autosomal - shows as a typical English ancestry. Tested with 23andMe, FTDNA
vineviz
Old Hand
****
Offline Offline

Posts: 191


« Reply #1 on: August 04, 2012, 09:40:10 AM »

Could some SNPs be placed on a chip which cannot be found via Sanger testing? Or is it necessary for there to be (basically the same) primers which are needed for Sanger testing to develop each individual probe for the chip?

I'm wondering (out loud) if there may end up some SNPs on the Nat Geno 2.0 chip which FT-DNA cannot make available (due to primer-related issues)

Yes, assay chips can  and do include SNPs that won't work in Sanger testing.
Logged
wing_genealogist
Senior Member
***
Offline Offline

Posts: 82


WWW
« Reply #2 on: August 04, 2012, 10:07:38 AM »

It'll definitely be interesting to see what SNPs appear in the Nat Geno 2.0 chip. Here's to hoping a good bunch of SNPs still unavailable from FT-DNA do show up!!
Logged

Y-DNA - R1b M157.2 (a private/family subclade of Z6/Z352) 111 markers tested

mt-DNA - J1c2g with the following private mutations: 315.1C 522.1A 522.2C C9974T C16256T (FMS tested and submitted to GenBank)

Autosomal - shows as a typical English ancestry. Tested with 23andMe, FTDNA
Pages: [1] Go Up Print 
« previous next »
Jump to:  


SEO light theme by © Mustang forums. Powered by SMF 1.1.13 | SMF © 2006-2011, Simple Machines LLC

Page created in 0.218 seconds with 18 queries.