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General Forums - Note: You must Be Logged In to post. Anyone can browse. => Mitochondrial DNA => Topic started by: Maliclavelli on December 08, 2011, 10:58:03 AM

Title: An interesting U5b3a2 from GenBank
Post by: Maliclavelli on December 08, 2011, 10:58:03 AM
Gioiello wrote on “Dienekes’ Anthropology blog”: thread “Finally an updated look at Y-chromosome of Jewish priests (Hammer et al. 2009)”:

“Maliclavelli wrote on “In an epoch of low population’s expansion, 7,450 YBP is the date when this population took agriculture from the Middle Eastern J2’s and G2’s and began to expand. Of course this population were the R1b1b2 of the Italian refugium, who, from 12,300 years ago, as the mitochondrial U5b3, have had a low expansion to Middle East till Mesopotamia and Iran, but was who remained in Italy or nearby who peopled Europe”.
The recent demonstration that Middle East lacks haplogroup R-L23- is easily explaining if we look at the map of the expansion from the Italian refugium of the mtDNA haplogroup U5b3: it lacks in Middle East too, then what could be understood as a following lost was probably an obstacle that prevented from the diffusion. We shouldn’t forget that Middle East was depopulated during the Younger Dryas[…] But I think isn’t supposable a migration from Europe to Middle East in that time, which was the time of a migration on the contrary, from Asia Minor to Balkans and Europe. If a migration there was I think it happened before, just after the Younger Dryas, in the time when it is documented that mtDNA U5b3 migrated” .

Now an interesting FGS U5b3a2 has been published by GenBank (see Ian Logan’s spreadsheet):

35. JQ074232(Greece/Jewish) FTDNA U5b3a2 07-DEC-2011   
A73G C150T A263G 315.1C A750G A1438G A2706G T3197C A4769G  C7028T G7226A A7768G A8860G G9477A A10978G A11467G G11719A A12308G G12372A T13617C T14182C C14383T C14766T A15326G C16192T C16270T G16391A

Of course this haplogroup came from the Italian Refugium like the paper of Pala et al.(Mitochondrial Haplogroup U5b3: A Distant Echo of the Epipaleolithic in Italy and
the Legacy of the Early Sardinians, The American Journal of Human Genetics, Volume 84, Issue 6, 814-821, 04 June 2009) has demonstrated, even though there is some divergences about its dating.
It has two mutation (14383T and 16391A) respect the other known haplotypes and only with other samples we’ll be able to say something more careful about its origin:
1)   a presence in Middle East from the migration from Italy many thousands of years ago, then the belonging to the ancient Jewish ancestry
2)   a more recent introgression from elsewhere.

Title: Re: An interesting U5b3a2 from GenBank
Post by: ToddiDean on December 24, 2011, 05:01:58 AM
Nice information.

Title: Re: An interesting U5b3a2 from GenBank
Post by: James morris on January 30, 2012, 05:36:04 AM
Something different!

Title: Re: An interesting U5b3a2 from GenBank
Post by: ethoward on August 19, 2015, 08:23:20 AM
I belong to U5b3a2 but haven't been able to find any information about it, or find any matches.  My mother's family were from Iceland.  Would love to learn more.