|165186||Paul Emile Nadon||H||16189C,16497G,16519C|
|175743||Ronald Bedard||H||16519C||263G, 309.1C, 315.1C, 507C|
A hypervariable region (HVR) is a location within nuclear DNA or the D-loop of mitochondrial DNA in which base pairs of nucleotides repeat (in the case of nuclear DNA) or have substitutions (in the case of mitochondrial DNA). Changes or repeats in the hypervariable region are highly polymorphic.
There are two mitochondrial hypervariable regions used in human mitochondrial genealogical DNA testing. HVR1 is considered a "low resolution" region and HVR2 is considered a "high resolution" region. Getting HVR1 and HVR2 DNA tests can help determine one's haplogroup. HVR1 locations are numbered 16001-16568. HVR2 locations are numbered 001-574.
Your HVR1 results will allow you to predict your mtDNA Haplogroup. Haplogroups are ancient family lines that can be traced back over 100,000 years and allows you to trace your ancestry back to ancient origins. This deep ancestry is a look at our ancient ancestral roots from tens of thousands of generations ago and shows how all people living today are connected to an ancient ancestor who lived in Africa over 100,000 years ago. To date, over 28 major mtDNA Haplogroups have been identified, and a unique set of mutations are associated to each mitochondrial DNA Haplogroup. The HVR1 region of your mtDNA contains a high concentration of ancestral markers, and thus the HVR1 test is informative enough to be used “stand-alone” for comparison to others and to make mtDNA Haplogroup predictions to gain information about an individual’s ancient ancestry. All of the other mtDNA test types serve to supplement the results of the mtDNA HVR1 test.