SNPs are Coming!

Updated  11-14-13

This article was originally written 11-19-11.  I am expecting the "Big Y" that was released earlier this week to give us branching within Lineages.  Stay tuned to see how things come out - and enjoy reading this two year old look forwards (towards now).  Terry

End of 11-14-13 Update

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For more than 10 years, we have made rapid and useful progress in using yDNA for our genealogical research.  This work has mainly been through ySTR - "markers" - that are tested by the commercial companies.  If you test at FTDNA (like I do), you are familiar with 25, 37, 67 and maybe even 111 markers.  A steady increase in the number of markers has helped us refine our understanding of who we match - and who we don't match.  We've struggled with "false matches" at 12 and 25 markers, upgraded to 37 and 67 markers to confirm our matches and used shared mutations to identify branching within our genetic family (often called a "Lineage" or "Group") 

Now, we seem to be on the verge of genealogical assistance from another part of the y-Chromosome - the SNP (Single Nucleotide Polymorphism).  A SNP is a mutation that occurs "once in history" and is passed down to all of the male descendants of the man who first had the mutation.  As the centuries have passed, these SNPs have built up in a logical progression that has allowed scientists to catalog them and then deduce their place in the history of man.  As the knowledge of SNPs expanded, scientists were able to use them to discern the branches on the "Family Tree of Man" - branches that are called "Haplogroups".  

Initially, Haplogroups were assigned letters of the alphabet as the defining SNPs were discovered - so there is no logic in which branch received which name.  If you have been involved with the use of DNA for Genealogy for very long, you can remember when Haplogroups were very short - like I1, I2, G, R1a, R1b, etc.  After 5 years, my own Haplogroup had lengthened from "R1b" - by one digit - to "R1b1".  While we have focused on our marker and surname based research, the identification of SNPs has exploded - which means that Haplogroups have gotten much longer - indicating more and more branching that has been discovered.  Currently, my own Haplogroup has extended to R1b1a2a1a1b3c2 - much longer that "R1b1" from the early days!

Despite the explosion of SNPs, the branching still hasn't reached into the marker territory - as a typical Lineage (Group) still has the same Haplogroup as many other Lineages across many surname families.  A few Lineages, like my own Barton Lineage I have their own unique SNP - but that is still very rare. 

But look out!!!!  The SNPs are coming!!  I can't visualize whether it will be less than a year, one year, or a "few" years - but it is clear that the time is coming when Haplogroups will be branching within Lineages.  We'll be seeing more and more Lineages with their own defining Haplogroup and will also will be seeing multiple Haplogroups with a Lineage.  As the SNP research fulfills its possiblitilies, we should see Haplogroup branching tracking into historic times and connecting with our known paper trails. 

What will this mean to each of us?  It's too early to be certain, but there seems to be a good chance that SNP defined Haplogroups will be able to replace those lost paper trails and allow us to understand how we are related.

I can't wait!

Terry

SNPs are coming!

Terry,

Thanks very much for your confirmation of what I thought I was seeing happen in the past few months. I don't understand the fine art but I understand what I see happening on the forums.

Your forthright article feels like a breath of fresh air to me and I appreciate your publishing it here for us.

Linda McKee
McKee Group

SNPs are coming

I'm type I1d1 who participated in Walk Thur the Y, received 25 SNPs of which 13 were significant in identifying my subclades. I've wondered what the others have been doing? Here they are:
L15 G+
L16 A+
L186 del+
L187 T+
L74 T+
M139 del+
M294 T+
M42 T+
M89 T+
P123 C+
P158 T+
PAGE.S00026 A+
Thanks Gary JULIAN of JULIAN Surname Project kit 18647

Warman family

how is Christopher Mercer and Warman Family related as it says an exact match

Warman family

I encourage you to take the specifics of your match to your project administrator.  There is insufficient information in your query for any sort of reply

Terry

SNPs are coming!

From what I can see on the R-L21 forum, and as you predicted earlier, it appears that the new tests, like the Big Y, are finding lots more SNPs, and adding to the 'phylogenetic tree'. For instance, on one of my lines (Newell) I was P312+L21+DF49+DF13+Z253-U152-U106-SRY2627-P66-M65-M37-M222-M153-L96-L526-L226-L195-L193-L192.1-L159.2-L144-L130-DF23-DF21-. that is to say, I had deep clade tested and found some SNPs, and individually tested more SNPs, getting down the line from P312 to L21 to DF13 to DF49. From there I had nothing else to test because I was negative for DF23 which was just below DF49.

With these new tests, there are new SNPs found below DF49 other than DF23, so I can now test further and get my Newell line more defined. Many more test results should be issued in the next two months. It will certainly be interesting to see how the phylogenetic tree expands!

My McCalip line descends a bit differently. Instead of P312 to L21, it goes to DF27, and there are several I still need to test for below that.

Y DNA G

I am located on the FT chart @ Z126 CTS4803