One of the goals of the X-chromosome Project website is to provide a centralized place for people to submit and compare X DNA test results. There are three ways that you can participate in this research:1) For genome-scan tests (23andMe and DeCODEme), complete the following steps:
a) Send me a private message providing me with your e-mail address. I will then e-mail you an Excel spreadsheet for you to use to submit your results, which you can return to me. If you do not have the capability to use an Excel spreadsheet, send me a PM anyway and I will explain to you how to submit your results via an alternate method. I will not share your e-mail address with anyone without your permission.
b) Log onto your personal page at www.23andme.com/you/
c) Click the “Browse Raw Data
” link near the top of the left-hand navigation bar
d) Click on the icon of the X chromosome
e) Scroll to the bottom of the page and click “Next>>
”. This will change the URL in your browser’s address bar to a form that you can edit with the start position of the block of interest.
f) Backspace over the number after the = sign in the URL, and replace it with the start position (not the SNP number that starts with “rs,” but the position number). On some browsers, you may be able to just double-click on this number to select just that portion of the URL, and then type the new position number in its place.
g) Press your <enter> key, and this will bring up a page showing the sequence of SNPs that begin with the start number that you specified.
h) Type the string of nucleotide base letters in the “<your name>’s Genotype
” column into the spreadsheet that I have sent you. Those of you who are good with spreadsheets may wish to first cut-and-paste the data into a text-only file, then import it into a new spreadsheet, and then simply paste the data from your spreadsheet into mine.
For privacy reasons, the haploblocks posted in this spreadsheet should not contain any genes (I will leave it up to each contributor to ensure that it doesn’t—if you are in doubt, make sure you look for the word “intergenic
” before each SNP number that you are submitting from your raw data list), so there should be minimal privacy risks. As a caveat, there are long sequences of DNA in between the SNPs sampled by 23andMe, which could potentially turn out to contain genes after further research, so submit your data at your own discretion. The spreadsheet that I will send you has the positions of genes marked with xx's, so leave those cells blank.
After you return the spreadsheet to me, I’ll add that data to the project results page.
If you have a new haploblock for which you want to solicit contributions, please post it in as a new topic on this forum board (again, first making sure that it doesn’t include any genes) and I’ll add it to the spreadsheet along with people’s data contributions, as they come in.
You may instead want to download you entire raw data file (using the “download raw data
” link near the upper right corner of the Browse Raw Data window), and then import it into a spreadsheet, to make it easier for you to find and extract SNP sequences.2) Another way that you can contribute your genome scan results
is by submitting your entire raw data file (edited to only include the X chromosome), to Ben Moscia, who is maintaining a spreadsheet of people’s X DNA data. If you are a male and submit your data to Ben, you do not need to also submit it to Project as described above, as I will automatically anonymously extract the relevant DNA blocks and copy them over to the project results chart. Please note that I only do this automatic data extraction for males, due to technical limitations with female DNA datasets.
The following instructions are copied (slightly modified to fit the forum format) from Ben’s signature over at DNA-forums:The following links are for people who want to contribute to or download the X-Chromosome 23andme file. To contribute, email me the x-portion of your raw 23andme file in .txt format. The data will be anonymous on the sheet. If you would like me to include your family origins, please include them in your email. To download the excel spreadsheet, click the link below. A file in .zip format is now included.
Email Ben here:
benmoscia AT hotmail.com
23andme X-chromosome spreadsheet can be found here:
23andme X-file in .zip format is here:
Please note that if you are submitting your entire X chromosome’s raw data to this spreadsheet, you are effectively submitting private medical information for public viewing (including any gene mutations that may make you susceptible to certain medical conditions), so do not submit your data there if this is a concern to you. Ben will anonymize your data and replace your name with a code number though, so the risk should be minimal unless you choose to share your name non-anonymously.When you submit your data, it is very important that you provide your ancestry percentages (assuming you know who at least some of your ancestors were), for your X-chromosome ancestors only. You can figure these percentages using one of the charts on the following website:
The following chart may be easier to use if you are a male (and can only be used by males):
You don't need to know every one of your ancestors to estimate the percentages--just fill in as much as you can, and then add up the percentages from the outermost boxes that you were able to fill in, and make sure they total 100% (e.g., 50% Swedish / 25% Irish / 25% French).
If anybody would care to explain the equivalent data extraction procedure for DeCODEme, I will add a link to your post in this thread.Also note that I will not routinely automatically extract your data from Ben’s file and add it to the haploblock datasets for people who are listed non-anonymously (i.e., using your actual name instead of an anonymous ID number), so you will still need to send me those separate sequences (using the instructions in part #1 above) if you wish to be included in those blocks. 3) There is a separate results spreadsheet for submitting results from X-STR testing,
which you can request from me by sending me a PM. See here for additional information and a link to the results page:http://www.worldfamilies.net/forum/index.php?topic=8448.0