John Walden has written some interesting posts on Rootsweb. This is the question:
1) By Geno 2.0 he got the mutation CTS6519.
“That data is just what I need to check on my CTS6519 mutation T-> C
Ancestral is 1 AGCAGTTGTCCTGAATTAATCGG
|WALDEN 1 AGCAGTTGTCCCGAATTAATCGG
Y-Position NCBI36 15471907
Y-Position GRCh37 16962513
Is there a way I can get access to the data to see if I can find a
connection to CTS6519?”
2) Greg Magoon wrote: “Hi John,
This mutation (b37 16962513 T->C) is found in a P312+ sample from Tuscany,
Italy (population code TSI) with the name NA20770”.
a) Reynolds replied: “John,
How do you know that you are P312-? I looked at the your Walden
subgroup in the Walden project at FTDNA and did not see any P312
b) Also Ann Turner intervened: “John, do you have results from 23andMe for rs34276300? A is the derived value”.
c) Walden: “Yes my 23andMe data shows rs34276300 Y 22157311 A
Which is P312 + so that means there are two known men with P312+ and
CTS6519+. One is Italian and one is American of oral history from Scotland
Right? Does that make this a candidate for a Subclad of P312?
Given what FTDNA/Geno 2.0 reports about me, that is I am P310, I conclude
they have not tested P312”.
d) Greg Magoon gave the haplotree: “I would classify NA20770 as DF27+ (more specifically, Z2564-Z2567+, which should be downstream of DF83 and others, which, in turn should be downstream from DF27:https://docs.google.com/spreadsheet/ccc?key=0Agq_ez43qXCjdFlxemtlUnZ1Qk01cVhMRVBFcm5WX3c&authkey=CIOag_UD&authkey=CIOag_UD#gid=27
This mutation (b37 16962513 T->C) appears to be downstream from Z2562-Z2563
and is likely either phyloequivalent with Z2564-Z2567 or downstream of
them. (The other Z2564-Z2567+ sample, HG00739, has a 'no-call' here.)”
3) I give the ancestral origin: Tuscany (Italy).