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Author Topic: National Geographic and Family Tree DNA Announce Geno 2.0  (Read 29862 times)
Diana
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« Reply #100 on: October 13, 2012, 04:42:06 PM »

  Okay so even if you did the conversion one would still need to purchase the kit full price is that right?  The last part of your reply was cut off...

  Thank you much!

@Diana,

All Nat Geno tests have to be ordered from the National Geographic Society.

http://shop.nationalgeographic.com/ngs/browse/productDetail.jsp?productId=2001246&gsk&code=MR20936

There was a $30  but only those folks who actually purchased the 1.0 test directly from NGS (rather than the folks who converted from FTDNA for the $15 fee) was eligible for the .
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R1b1a2a1a1b3 U152+ Z56+ Z144/Z145/Z146+ P312+ U106- M228.2- M160- M126- L4- L21- L2- L196- L176.2- DYS492=14 Roma, Italia.
wing_genealogist
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« Reply #101 on: October 13, 2012, 05:28:45 PM »

Oops, sorry about the cutoff.

Yup, even if you did the conversion, you would still need to purchase at the full price.


Ray
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Y-DNA - R1b M157.2 (a private/family subclade of Z6/Z352) 111 markers tested

mt-DNA - J1c2g with the following private mutations: 315.1C 522.1A 522.2C C9974T C16256T (FMS tested and submitted to GenBank)

Autosomal - shows as a typical English ancestry. Tested with 23andMe, FTDNA
1790Noll
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« Reply #102 on: October 14, 2012, 03:36:37 AM »

Yes i purchased the geno 2.0 kit with _discount because i sent my NG first phase code..
Also i am N9198 at Ftdna..
 
Today My order it's always in process..
I await.. when will be .. in Itay..

I am L20+ and i  looking forward to be able to compare the data with those of Gilbert ,, other L20+..

I always have to thank both Gilbert and Rocca and Feher, such as project administrators U152+, for all their exciting work and advice they have given to me ..
 
Does anyone know if NG are starting to ship the kit geno 2.0 also  in Europe?

Ciao from Italy..
Giuseppe - Joseph  (Bolgeris)
« Last Edit: October 14, 2012, 03:39:12 AM by 1790Noll » Logged
1790Noll
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« Reply #103 on: October 17, 2012, 12:20:43 PM »

Today....my geno 2.0 shipped to Italy...  !!

Order Tracking

Date Placed: 5-set-2012
Status: Shipped
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Richard Rocca
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« Reply #104 on: October 17, 2012, 12:40:58 PM »

Today....my geno 2.0 shipped to Italy...  !!

Order Tracking

Date Placed: 5-set-2012
Status: Shipped


That's great news Giuseppe. Just an update on my kit - Nat Geo has received it and is now showing in the "DNA Isolation" phase.
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seferhabahir
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« Reply #105 on: October 17, 2012, 01:32:01 PM »

UPS tracking shows that my third cousin has received his Geno 2.0 kit. Unfortunately, he is not on my direct Y-DNA line, but this cousin is a direct male descendent of my paternal great-grandfather's wife's paternal grandfather. So this great-great-great-grandfather would be my oldest documented ancestor on any line, born around 1800. Will be interesting to see what his Y-DNA haplogroup turns out to be.
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Y-DNA: R-L21 (Z251+ L583+)

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wing_genealogist
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« Reply #106 on: October 19, 2012, 03:27:09 PM »

I am coordinating a Nat Geno 2.0 testing spreadsheet for the U106 Project. I am looking for someone who is L11+ but U106- to add to this spreadsheet. Having someone outside of U106 hopefully will help us identify which new SNPs would fall under U106 and which will fall above U106.

Is there anyone on this forum who would be willing to serve in this capacity for us?  

Thanks in Advance,

Ray

feel free to contact me at: wing_genealogist AT yahoo DOT com
« Last Edit: October 19, 2012, 03:27:49 PM by wing_genealogist » Logged

Y-DNA - R1b M157.2 (a private/family subclade of Z6/Z352) 111 markers tested

mt-DNA - J1c2g with the following private mutations: 315.1C 522.1A 522.2C C9974T C16256T (FMS tested and submitted to GenBank)

Autosomal - shows as a typical English ancestry. Tested with 23andMe, FTDNA
1790Noll
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« Reply #107 on: October 21, 2012, 03:32:40 AM »

I asked to Natgeo if it was possible to trace the shipment of the geno 2.0 kit ..
and this was the answer, which shows that the European kits are shipped from the UK.

"We would be happy to assist with your inquiry. Your order .... was shipped from our UK store,  unfortunately we do not have any tracking information for this order".

So i remain confident waiting for the 2.0 gen kit.

ciao.
« Last Edit: October 21, 2012, 03:33:11 AM by 1790Noll » Logged
Solothurn
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« Reply #108 on: October 22, 2012, 12:21:48 PM »

This I didn't know!

Can you please tell me, what shipping method you will be using to return the kit?

Thanks




"Your order .... was shipped from our UK store,".


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1790Noll
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« Reply #109 on: October 22, 2012, 02:06:26 PM »

I ordered geno 2.0 ..
Geno 2.0 - Genographic Project Participation and DNA Ancestry Kit, Europe & Australia Delivery
It was for european shipment..
There were only one shipment.. to Europe & Australia..  
ciao.
« Last Edit: October 25, 2012, 12:51:05 PM by 1790Noll » Logged
1790Noll
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« Reply #110 on: October 24, 2012, 12:23:33 PM »

Finally 24 oct I have taken to my nearest post office my geno 2.0  kit.
The package is being shipped on October 12, from Essex UK. And was received on 23 October. I think it's a normal time of delivery, for an expedition sent by ordinary mail.
25 oct i sent the kit in the U.S.A.
Ciao.
Giuseppe
« Last Edit: October 25, 2012, 12:50:37 PM by 1790Noll » Logged
Newragh
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« Reply #111 on: October 27, 2012, 10:29:43 PM »

I just sent in my DNA sample to Geno 2.0 and hope that there is some new granularity within M222.

I think that for the general R1b problem to be solved, a special case, like Ireland, must be solved first. Ireland being special because it has been generally isolated since the Common Era began.

I am not as knowledgeable with respect to DNA studies as the people on this forum are, which is why I read it and the old DNA-forum as well as EU Pedia. My background is in Mathematics and I can only approach the problem from that perspective.

There are only three new population candidates in the past 2000 years and they seem all to be well defined.

The Ulster Plantation: Their descendants are identified with no ambiguity.
The Vikings: It seems the consensus that they added only a small amount to the Irish gene pool. There was a discussion on EU Pedia recently to the effect that prominent Irish families adopted Norse names for their children like Manus and Ragnal. So a Mac Manus didn't mean a Norse family, only an Irish family who liked novel names.
Cambrio-Normans: This is not immediately solvable, but with the proper DNA testing of the known descendants of the original lines, the Norman line may well be distinguishable from the native Irish tenants who later took their name.

The landowner of my gg-grandfather from Louth was called Lord Louth and was a Plunkett who was a relative of Saint Oliver Plunkett. As late as 1900, there was a beautiful Lady Louth who graced the cover of some horsey magazine. Her male descendants should be easily identified and hopefully tested.

It seems reasonable that many of the prominent Norman families have known descendants and their data could be used to extrapolate the missing families.

So I think that Ireland is solvable with enough testing. This assumes that the work that has been done in the past few years about the non-M222 sub clades of L21 continues.
« Last Edit: October 27, 2012, 10:31:20 PM by Newragh » Logged

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gtc
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« Reply #112 on: October 28, 2012, 11:07:09 AM »

So I think that Ireland is solvable with enough testing.

I agree, and hopefully the Irish DNA Atlas project will go a long way in that regard:

http://www.familyhistory.ie/docs/DNA/DNA_01.pdf

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Y-DNA: R1b-Z12* (R1b1a2a1a1a3b2b1a1a1) GGG-GF Ireland (roots reportedly Anglo-Norman)
mtDNA: I3b (FMS) Maternal lines Irish
brunetmj
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« Reply #113 on: October 28, 2012, 05:11:05 PM »

I received 2 emails from national geographic . The first acknowledged my kit was received and the 2nd , a few days later, that the 2nd step, DNA isolation , has begun .
So far it appears they are good about notifications .
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aidan
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« Reply #114 on: October 29, 2012, 02:35:39 PM »

I ordered the test on July 31st and it still hasn't shipped. It says 'In Process'. Has anyone else from Ireland received their kit yet?
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chris1
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« Reply #115 on: October 29, 2012, 03:54:16 PM »

The landowner of my gg-grandfather from Louth was called Lord Louth and was a Plunkett who was a relative of Saint Oliver Plunkett. As late as 1900, there was a beautiful Lady Louth who graced the cover of some horsey magazine. Her male descendants should be easily identified and hopefully tested.

There is a distinctive (STR modal) group of 11 related Meath/Louth Plunketts with 67 markers who are said on the Plunkett DNA Project to probably be related to Saint Oliver. It doesn't look like they are actively testing newer SNPs, however. One (58900) is U152- and U106- but no sign of L21 or DF27 having been tested on the project's SNP table.

http://www.familytreedna.com/public/Plunkett/default.aspx?section=yresults
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gtc
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« Reply #116 on: October 30, 2012, 03:25:44 AM »

There's an article on an Italian website mentioning Geno 2.0, Spencer Wells and Luca Cavalli-Sforza and results being presented on Nov. 9 in Florence, as part of Florens 2012 - International Biennial of cultural and environmental assets.

Google's translator doesn't help me determine if said presentation features more results from Geno 1, or details of Geno 2.0, or both.

Perhaps somebody here with Italian language skills can help clarity that.

http://www.ilsole24ore.com/art/tecnologie/2012-10-27/quei-link-uniscono-percorsi-180853.shtml?uuid=AbNjOUxG
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Y-DNA: R1b-Z12* (R1b1a2a1a1a3b2b1a1a1) GGG-GF Ireland (roots reportedly Anglo-Norman)
mtDNA: I3b (FMS) Maternal lines Irish
Heber
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« Reply #117 on: October 30, 2012, 07:03:07 AM »

There's an article on an Italian website mentioning Geno 2.0, Spencer Wells and Luca Cavalli-Sforza and results being presented on Nov. 9 in Florence, as part of Florens 2012 - International Biennial of cultural and environmental assets.

Google's translator doesn't help me determine if said presentation features more results from Geno 1, or details of Geno 2.0, or both.

Perhaps somebody here with Italian language skills can help clarity that.

http://www.ilsole24ore.com/art/tecnologie/2012-10-27/quei-link-uniscono-percorsi-180853.shtml?uuid=AbNjOUxG


Here is the NG slot for the Florence conference (Nov 9).
ore 15.00 - 18.30
Deep ancestry: inside the genographic project
a cura di National Geographic
organised by National Geographic

The timing makes sense. It is the day before the FTDNA conference in Houston (Nov 10-12).
Dr. Wells is scheduled to join that conference by Skype to talk about Geno 2.0.

http://www.familytreedna.com/conference/

It also corresponds to the American Society of Human Genetics conference in SF (Nov 6-10).

http://www.ashg.org/2012meeting/abstracts/fulltext/index.shtml

This ASHG event has several interesting papers. I look forward to the new Ancestry Painting 2.0 using 20 reference populations and will be interested to see the European reference populations they use? I would also like to see a detailed breakdown of the sampled group if possible by haplogroup and origin.  
I am very interested in the People of the British Isles, POBI paper in the same conference. This is a follow up from the Summer exhibition in the Royal Academy. Hopefully this time we will get the detailed Genetic Atlas of Britain. I am participating in the Irish DNA Atlas project so I will be interested in eventually comparing results when that study is published. What is interesting is they have compared the results to reference European populations. Which populations remains to be seen.

All in all an interesting week for Genetic genealogy.
« Last Edit: October 30, 2012, 07:20:45 AM by Heber » Logged

Heber


 
R1b1a2a1a1b4  L459+ L21+ DF21+ DF13+ U198- U106- P66- P314.2- M37- M222- L96- L513- L48- L44- L4- L226- L2- L196- L195- L193- L192.1- L176.2- L165- L159.2- L148- L144- L130- L1-
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gtc
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« Reply #118 on: October 30, 2012, 10:32:18 AM »

There's an article on an Italian website mentioning Geno 2.0, Spencer Wells and Luca Cavalli-Sforza and results being presented on Nov. 9 in Florence, as part of Florens 2012 - International Biennial of cultural and environmental assets.

Google's translator doesn't help me determine if said presentation features more results from Geno 1, or details of Geno 2.0, or both.

Perhaps somebody here with Italian language skills can help clarity that.

http://www.ilsole24ore.com/art/tecnologie/2012-10-27/quei-link-uniscono-percorsi-180853.shtml?uuid=AbNjOUxG


Here is the NG slot for the Florence conference (Nov 9).
ore 15.00 - 18.30
Deep ancestry: inside the genographic project
a cura di National Geographic
organised by National Geographic

The timing makes sense. It is the day before the FTDNA conference in Houston (Nov 10-12).
Dr. Wells is scheduled to join that conference by Skype to talk about Geno 2.0.

http://www.familytreedna.com/conference/

It also corresponds to the American Society of Human Genetics conference in SF (Nov 6-10).

http://www.ashg.org/2012meeting/abstracts/fulltext/index.shtml

This ASHG event has several interesting papers. I look forward to the new Ancestry Painting 2.0 using 20 reference populations and will be interested to see the European reference populations they use? I would also like to see a detailed breakdown of the sampled group if possible by haplogroup and origin.  
I am very interested in the People of the British Isles, POBI paper in the same conference. This is a follow up from the Summer exhibition in the Royal Academy. Hopefully this time we will get the detailed Genetic Atlas of Britain. I am participating in the Irish DNA Atlas project so I will be interested in eventually comparing results when that study is published. What is interesting is they have compared the results to reference European populations. Which populations remains to be seen.

All in all an interesting week for Genetic genealogy.

It sure is an interesting week, and I'll be counting down the days.

The PoBI paper is keenly awaited by a very large number of people and, among other things, I'm hoping that it may ultimately spur interest from European countries to carry out similar major projects with their own populations.

The European reference population (IIRC) numbers some 6,500 samples. It will indeed be interesting to learn the spread and depth of those.
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Y-DNA: R1b-Z12* (R1b1a2a1a1a3b2b1a1a1) GGG-GF Ireland (roots reportedly Anglo-Norman)
mtDNA: I3b (FMS) Maternal lines Irish
saje
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« Reply #119 on: November 01, 2012, 02:44:51 PM »

How in depth does Geno test for your haplogroup?  Does it test all markers downstream? 

Thanks
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Heber
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« Reply #120 on: November 01, 2012, 03:48:23 PM »

How in depth does Geno test for your haplogroup?  Does it test all markers downstream?  

Thanks


From Bennet Greenspan's Q&A on the announcement of Geno 2.0.

"Q:  Does Family Tree DNA plan to offer a test that will be more extensive then the new Genographic test for the Y chromosome?

A:  No. The most extensive test for obtaining YDNA SNP data is available on the Geno 2.0 chip and Family Tree DNA has no plans to compete with its partner.  STR results will not be supplied by Geno 2.0 and all regular genealogical marker tests should be ordered through Family Tree DNA.  These two tests go hand in hand.

By way of example, in haplogroup R-M222 – the new Geno chip includes discoveries of at least three unique SNP’s downstream of R-M222.

These 10,000 new SNPs will provide, for almost everyone, one or two additional clades (subhaplogroups) down the tree from where they are located today.  For some people, these will reach into a genealogical timeframe, connecting their SNPs and their STR data.  The STR tests will then be used to further augment the Geno 2.0 SNP tests for genealogical comparisons within families."

Roberta's blog on the announcement is really very good.

http://dna-explained.com/2012/07/25/national-geographic-geno-2-0-announcement-the-human-story/

The first results should start coming in before the holidays and I hope the detailed paper will be published around the 9th November, when Spencer Wells discusses it at two events. The real work will then begin identifying the new SNPs from the expanded customer base and placing them correctly in the Phylogenic Tree and priming subsequent versions of the chip.
Just based on the current test base alone of 900 Y chromosome kits, the haplotree expanded from 862 SNPs to a total of 6153. Imagine what it will do with another 1000 or 10,000 or 100,000 tests.
« Last Edit: November 01, 2012, 04:18:12 PM by Heber » Logged

Heber


 
R1b1a2a1a1b4  L459+ L21+ DF21+ DF13+ U198- U106- P66- P314.2- M37- M222- L96- L513- L48- L44- L4- L226- L2- L196- L195- L193- L192.1- L176.2- L165- L159.2- L148- L144- L130- L1-
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Heber
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« Reply #121 on: November 04, 2012, 06:55:00 AM »

There will be a poster presentation of the new Geno 2.0 chip at next weeks ASHG conference in SF.
There are also several separate poster presentations of case studies using the platform.
No indication if the detailed set of SNPs will be published, which is disappointing.

The GenoChip: a new tool for genetic anthropology
Title: The GenoChip: a new tool for genetic anthropology.(3377W) (2:15PM-3:15PM on Wed) (Poster)
Author(s): S. Wells, E. Greenspan, S. Staats, T. Krahn, C. Tyler-Smith, Y. Xue, S. Tofanelli, P. Francalacci, F. Cucca, L. Pagani, L. Jin, H. Li, T. G. Schurr, J. B. Gaieski, C. Melendez, M. G. Vilar, A. C. Owings, R. Gomez, R. Fujita, F. Santos, D. Comas, O. Balanovsky, E. Balanovska, P. Zalloua, H. Soodyall, R. Pitchappan, G. Arun Kumar, M. F. Hammer, B. Greenspan, E. Elhaik

"Background: The Genographic Project is an international effort aimed at charting human history using genetic data. The project is non-profit and non-medical, and through the sale of its public participation kits it supports cultural preservation efforts in indigenous and traditional communities. To extend our knowledge of the human journey, interbreeding with ancient hominins, and modern human demographic history, we designed a genotyping chip optimized for genetic anthropology research. Methods: Our goal was to design, produce, and validate a SNP array dedicated to genetic anthropology. The GenoChip is an Illumina HD iSelect genotyping bead array with over 130,000 highly informative autosomal and X-chromosomal SNPs ascertained from over 450 worldwide populations, ~13,000 Y-chromosomal SNPs, and ~3,000 mtDNA SNPs. To determine the extent of gene flow from archaic hominins to modern humans, we included over 25,000 SNPs from candidate regions of interbreeding between extinct hominins (Neanderthal and Denisovan) and modern humans. To avoid any inadvertent medical testing we filtered out all SNPs that have known or suspected health or functional associations. We validated the chip by genotyping over 1,000 samples from 1000 Genomes, Family Tree DNA, and Genographic Project populations. Results: The concordance between the GenoChip and the 1000 Genomes data was over 99.5%. The GenoChip has a SNP density of approximately (1/100,000) bases over 92% of the human genome and is highly compatible with Illumina and Affymetrix commercial platforms. The ~10,000 novel Y SNPs included on the chip have greatly refined our understanding of the Y-chromosome phylogenetic tree. By including Y and mtDNA SNPs on an unprecedented scale, the GenoChip is able to delineate extremely detailed human migratory paths. The autosomal and X-chromosomal markers included on the GenoChip have revealed novel patterns of ancestry that shed a detailed new light on human history. Interbreeding analysis with extinct hominids confirmed some previous reports and allowed us to describe the modern geographical distribution of these markers in detail. Conclusions: The GenoChip is the first genotyping chip completely dedicated to genetic anthropology with no known medically relevant markers. We anticipate that the large-scale application of the GenoChip using the Genographic Project’s diverse sample collection will provide new insights into genetic anthropology and human history."

http://abstracts.ashg.org/cgi-bin/2012/ashg12s
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Heber


 
R1b1a2a1a1b4  L459+ L21+ DF21+ DF13+ U198- U106- P66- P314.2- M37- M222- L96- L513- L48- L44- L4- L226- L2- L196- L195- L193- L192.1- L176.2- L165- L159.2- L148- L144- L130- L1-
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gtc
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« Reply #122 on: November 04, 2012, 07:48:40 AM »

Quote
No indication if the detailed set of SNPs will be published, which is disappointing.

I expect that sort of detail will be a supplement to a fully-fledged paper to be published in one of the big journals ... but when?
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Y-DNA: R1b-Z12* (R1b1a2a1a1a3b2b1a1a1) GGG-GF Ireland (roots reportedly Anglo-Norman)
mtDNA: I3b (FMS) Maternal lines Irish
Paul Burns
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« Reply #123 on: November 07, 2012, 05:38:18 PM »

I notice just now that that my Geno kit has been "promoted" from Stage 1 (20% complete)  to Stage 2 (40% "DNA Isolation"). Progress!
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Paul Burns
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« Reply #124 on: November 08, 2012, 03:33:35 AM »

There was a posting on the Genealogy-DNA Rootsweb list by Gary Miller, who attended the ASHG conference in San Francisco. His image of the Geno 2.0 handout is here:

http://www.millerfamilyhistory.com/geno2.jpg
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Heber


 
R1b1a2a1a1b4  L459+ L21+ DF21+ DF13+ U198- U106- P66- P314.2- M37- M222- L96- L513- L48- L44- L4- L226- L2- L196- L195- L193- L192.1- L176.2- L165- L159.2- L148- L144- L130- L1-
Paternal L21* DF21


Maternal H1C1



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