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Author Topic: National Geographic and Family Tree DNA Announce Geno 2.0  (Read 29044 times)
wing_genealogist
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« Reply #50 on: August 01, 2012, 05:56:51 PM »

My understanding (and I could well be wrong) is that if your DNA was used in the vetting project, NatGeo will automatically send you your results. There is nothing you need to do to access the sample. On the other hand, there is no way of knowing whether or not your DNA was actually used by NatGeo until they start shipping the orders and you either receive or fail to receive a notice from them.
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Y-DNA - R1b M157.2 (a private/family subclade of Z6/Z352) 111 markers tested

mt-DNA - J1c2g with the following private mutations: 315.1C 522.1A 522.2C C9974T C16256T (FMS tested and submitted to GenBank)

Autosomal - shows as a typical English ancestry. Tested with 23andMe, FTDNA
DavidCar
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« Reply #51 on: August 01, 2012, 06:19:59 PM »

I signed up for Geno 2.0, as also did someone else in my little Z346 SNP group.  So we'll see if there are any Y SNP differences.

I'm expecting Z346 is one of the SNPs tested in Geno 2.0.
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thetick
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« Reply #52 on: August 01, 2012, 08:06:18 PM »

I'm expecting Z346 is one of the SNPs tested in Geno 2.0. 

Not likely since the Z346 date is 2012-04-28 at http://ytree.ftdna.com/taxonomy_editor/log/index.php?name=Draft&node=99813444.  Thomas Krahn from FTDNA said any Y SNP discoveries after Nov 2011 will not be included in  Geno 2.0. 
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df.reynolds
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« Reply #53 on: August 01, 2012, 08:49:30 PM »

I'm expecting Z346 is one of the SNPs tested in Geno 2.0. 

Not likely since the Z346 date is 2012-04-28 at http://ytree.ftdna.com/taxonomy_editor/log/index.php?name=Draft&node=99813444.  Thomas Krahn from FTDNA said any Y SNP discoveries after Nov 2011 will not be included in  Geno 2.0. 
Z346 was known to Thomas and in his db in Nov 2011. The fact that it didn't get added to the Draft Tree until April is not relevant.

-david
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on the edge
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« Reply #54 on: September 15, 2012, 04:25:15 PM »

Can anyone please offer an opinion as to whether testing the Geno 2.0 would have any possible value for a DF13*? Thanks.
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wing_genealogist
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« Reply #55 on: September 15, 2012, 04:43:12 PM »

Can anyone please offer an opinion as to whether testing the Geno 2.0 would have any possible value for a DF13*? Thanks.

We really cannot say until either NatGeo publishes the SNPs on the chip or results become available.
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Y-DNA - R1b M157.2 (a private/family subclade of Z6/Z352) 111 markers tested

mt-DNA - J1c2g with the following private mutations: 315.1C 522.1A 522.2C C9974T C16256T (FMS tested and submitted to GenBank)

Autosomal - shows as a typical English ancestry. Tested with 23andMe, FTDNA
Heber
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« Reply #56 on: September 16, 2012, 07:29:14 AM »

Can anyone please offer an opinion as to whether testing the Geno 2.0 would have any possible value for a DF13*? Thanks.

For first time testers, absolutely yes. Spencer Wells have confirmed that there will be several SNPs below M222. For someone already confirmed DF13*, I would wait until the first results are in or the detailed paper is published. I understand the the detailed paper with confirmed SNPs will be published prior to availability of the test (end of October), so I would hold off for another month.
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Heber


 
R1b1a2a1a1b4  L459+ L21+ DF21+ DF13+ U198- U106- P66- P314.2- M37- M222- L96- L513- L48- L44- L4- L226- L2- L196- L195- L193- L192.1- L176.2- L165- L159.2- L148- L144- L130- L1-
Paternal L21* DF21


Maternal H1C1



Mark Jost
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« Reply #57 on: September 24, 2012, 07:58:28 PM »

Thomas posted a reply commentary on the Geno 2.0 to CeCe.
 
"The future of Y SNP testing after Geno 2.0 will be essentially:
 1.) Test Geno 2.0 or predict your Y haplogroup as good as possible from Y-STR results.
 2.) If necessary use individual Y-SNP tests to determine your fine haplogroup (to the last twig of the current knowledge if you want).
 3.) If you still can't solve a Y haplogroup question consider to apply for a WTY run and hopefully find a new SNP that will solve your question and/or contribute to further research and for inclusion in the next Geno Chip."
 
More details here:
 
http://groups.yahoo.com/group/DNA-NEWBIE/message/25166
 
MJost
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148326
Pos: Z245 L459 L21 DF13**
Neg: DF23 L513 L96 L144 Z255 Z253 DF21 DF41 (Z254 P66 P314.2 M37 M222  L563 L526 L226 L195 L193 L192.1 L159.2 L130 DF63 DF5 DF49)
WTYNeg: L555 L371 (L9/L10 L370 L302/L319.1 L554 L564 L577 P69 L626 L627 L643 L679)
rms2
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« Reply #58 on: September 24, 2012, 08:07:15 PM »

I feel pretty blessed to have gotten a positive hit on one of the new SNPs unearthed by the 1000 Genomes researchers.

I think things are going to get tougher and more expensive for awhile, especially once you reach finer and finer points of resolution.

Hopefully whole genome testing will become readily available at a fairly reasonable price sometime in the near future.
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Mark Jost
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« Reply #59 on: September 24, 2012, 08:34:21 PM »

Well I know I have spend wayyyyyyy to much of my funds for all of this but its putting in coins the machine knowing your going to get lucky and win a prize eventually.

But the DF13 x subclade guys will hopefully find a snp that will connect most of the smaller subclades with the Scots or the other big three.

MJost
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148326
Pos: Z245 L459 L21 DF13**
Neg: DF23 L513 L96 L144 Z255 Z253 DF21 DF41 (Z254 P66 P314.2 M37 M222  L563 L526 L226 L195 L193 L192.1 L159.2 L130 DF63 DF5 DF49)
WTYNeg: L555 L371 (L9/L10 L370 L302/L319.1 L554 L564 L577 P69 L626 L627 L643 L679)
Mike Walsh
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« Reply #60 on: September 24, 2012, 10:53:09 PM »

I feel pretty blessed to have gotten a positive hit on one of the new SNPs unearthed by the 1000 Genomes researchers.

I think things are going to get tougher and more expensive for awhile, especially once you reach finer and finer points of resolution.

Hopefully whole genome testing will become readily available at a fairly reasonable price sometime in the near future.

Unfortunately or not, knowledge with a little luck will certainly trump for a while. The replacement package tests, such as Geno 2.0, will lag behind develop of the actual Y phylogenetic tree do rifle shots will do better than shotgun blasts, or rather grenades is probably the better analaogy. If you know your target, good for you. Testing to at least 67 markers and joining projects will help you know your target.

WTY is, as Thomas says, another option, but he is right. It should be viewed as a contribution, There is a possibility of hitting gold.
« Last Edit: September 24, 2012, 11:04:58 PM by Mikewww » Logged

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Mark Jost
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« Reply #61 on: September 26, 2012, 01:04:50 PM »

I feel pretty blessed to have gotten a positive hit on one of the new SNPs unearthed by the 1000 Genomes researchers.

I think things are going to get tougher and more expensive for awhile, especially once you reach finer and finer points of resolution.

Hopefully whole genome testing will become readily available at a fairly reasonable price sometime in the near future.

Unfortunately or not, knowledge with a little luck will certainly trump for a while. The replacement package tests, such as Geno 2.0, will lag behind develop of the actual Y phylogenetic tree do rifle shots will do better than shotgun blasts, or rather grenades is probably the better analaogy. If you know your target, good for you. Testing to at least 67 markers and joining projects will help you know your target.

WTY is, as Thomas says, another option, but he is right. It should be viewed as a contribution, There is a possibility of hitting gold.

I also have to chime in here as well.

67 Markers is the mininum number I am suggesting now unless one has family groupings and there is at least two member tested to this or higher level to confirm family status. Surnames grouping may or may not be applicable.

Variety clustering based on haplotype markers is an important consideration of what SNP(s) would be recommended or a complete SNP testing using Geno2.0.

Geno2.0 replaces the existing DeepClade Test offered by FtDNA. There are almost 50 SNPs under L21 now, with around 10 to 12 of the newest discovered SNPs may not be included.

Here are the SNPs and dates added to the Draft Ytree which I complied to consider which ones may or may not have been added to the original Geno2.0 system with said 'Nov 2011' Cutoff.

L1066 8/10/2012
DF23  8/9/2012
DF63  6/26/2012
DF25  6/25/2012
DF41 6/13/2012
DF13  5/15/2012
Z255  3/9/2012
L908,L909 1/17/2012
L745 12/26/2011
L894,L895  12/5/2011
DF49   11/1/2011
L705,L706 10/24/2011

MJost
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148326
Pos: Z245 L459 L21 DF13**
Neg: DF23 L513 L96 L144 Z255 Z253 DF21 DF41 (Z254 P66 P314.2 M37 M222  L563 L526 L226 L195 L193 L192.1 L159.2 L130 DF63 DF5 DF49)
WTYNeg: L555 L371 (L9/L10 L370 L302/L319.1 L554 L564 L577 P69 L626 L627 L643 L679)
seferhabahir
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« Reply #62 on: September 27, 2012, 02:32:10 AM »

Any one else get the long-awaited email message from FTDNA in your inbox today? Apparently a lot of people did.

"...  As part of the development process, we tested your pre-approved sample to confirm the SNPs on the chip were working, and to help with the placement of your SNPs on the tree. Your sample was chosen based on other testing you had already done with Family Tree DNA, either the Walk the Y (WTY) or mtDNA full-genome sequencing (FGS) ...

Because your sample was used to help test the Geno 2.0 chip, your data - autosomal, mtDNA and Y (in the case of men) will be uploaded to the new National Geographic website at www.genographic.com later this fall. Therefore, there is no reason for you to order another Geno 2.0 kit to have yourself tested..."

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df.reynolds
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« Reply #63 on: September 27, 2012, 03:53:55 AM »

Any one else get the long-awaited email message from FTDNA in your inbox today? Apparently a lot of people did.

"...  As part of the development process, we tested your pre-approved sample to confirm the SNPs on the chip were working, and to help with the placement of your SNPs on the tree. Your sample was chosen based on other testing you had already done with Family Tree DNA, either the Walk the Y (WTY) or mtDNA full-genome sequencing (FGS) ...

Because your sample was used to help test the Geno 2.0 chip, your data - autosomal, mtDNA and Y (in the case of men) will be uploaded to the new National Geographic website at www.genographic.com later this fall. Therefore, there is no reason for you to order another Geno 2.0 kit to have yourself tested..."



Two DF21+ people did, that I am aware of. One R-L720 and an R-L627 (me).

-david
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Mike Walsh
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« Reply #64 on: September 27, 2012, 11:49:45 PM »


Any one else get the long-awaited email message from FTDNA in your inbox today? ...

"... Your sample was chosen based on other testing you had already done with Family Tree DNA, either the Walk the Y (WTY) or mtDNA full-genome sequencing (FGS) ...

Because your sample was used to help test the Geno 2.0 chip, your data - autosomal, mtDNA and Y  in the case of men) will be uploaded to the new National Geographic website ....

Two DF21+ people did, that I am aware of. One R-L720 and an R-L627 (me).

Let's keep a list of the kit #s so we can look for their results.  An L513/L193 guy also will get the free Geno 2.0 results - kit 130361 Elliott.
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wing_genealogist
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« Reply #65 on: September 28, 2012, 05:44:32 AM »

AFAIK no U106+ person has received a notice of free Geno 2.0 results. I have sent an email to the whole forum and have not heard any replies.

I am somewhat disappointed in this as there are a LOT of new SNPs below U106 (primarily discovered in the 1K Genome Project) and while at least some of them should be in the 2.0 chip, it does not appear where any of them were tested to assure they will receive reliable results.

EDIT:  I'm hoping Chris Tyler-Smith (who is credited as working with the National Geographic Project on the Y-DNA) actually had DNA samples from the 1K Genome project to work with, and used those samples to to verify the SNPs on the Geno 2.0 chip.
« Last Edit: September 28, 2012, 07:06:07 AM by wing_genealogist » Logged

Y-DNA - R1b M157.2 (a private/family subclade of Z6/Z352) 111 markers tested

mt-DNA - J1c2g with the following private mutations: 315.1C 522.1A 522.2C C9974T C16256T (FMS tested and submitted to GenBank)

Autosomal - shows as a typical English ancestry. Tested with 23andMe, FTDNA
razyn
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« Reply #66 on: September 28, 2012, 07:57:15 AM »

Since the Geno 2.0 test has been advertised as using NextGen technology that doesn't involve (or perhaps just doesn't require?) PCR amplification -- and FTDNA tells prospective buyers of Geno 2.0 that a different, fresh sample has to be provided for this test, thus disappointing several bloggers who had sent in samples from older relatives, now deceased -- I've sort of assumed that our original, bar-coded samples are stored at FTDNA after PCR amplification.

If that assumption is mistaken, and they've stored the little vials we sent them in an unamplified state, this bit about "your sample was used to help test the Geno 2.0 chip" would make more sense.  But then their published requirement of fresh samples makes less sense, to me.
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Richard Rocca
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« Reply #67 on: September 28, 2012, 08:40:37 AM »

Since the Geno 2.0 test has been advertised as using NextGen technology that doesn't involve (or perhaps just doesn't require?) PCR amplification -- and FTDNA tells prospective buyers of Geno 2.0 that a different, fresh sample has to be provided for this test, thus disappointing several bloggers who had sent in samples from older relatives, now deceased -- I've sort of assumed that our original, bar-coded samples are stored at FTDNA after PCR amplification.

If that assumption is mistaken, and they've stored the little vials we sent them in an unamplified state, this bit about "your sample was used to help test the Geno 2.0 chip" would make more sense.  But then their published requirement of fresh samples makes less sense, to me.

From what I've read, Geno 2.0 will not store the samples after sequencing them, so it would be a bad idea to send samples of the deceased from FTDNA to Geno 2.0.
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Mike Walsh
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« Reply #68 on: September 28, 2012, 02:53:39 PM »


Any one else get the long-awaited email message from FTDNA in your inbox today? ...

"... Your sample was chosen based on other testing you had already done with Family Tree DNA, either the Walk the Y (WTY) or mtDNA full-genome sequencing (FGS) ...

Because your sample was used to help test the Geno 2.0 chip, your data - autosomal, mtDNA and Y  in the case of men) will be uploaded to the new National Geographic website ....

Two DF21+ people did, that I am aware of. One R-L720 and an R-L627 (me).

Let's keep a list of the kit #s so we can look for their results.  An L513/L193 guy also will get the free Geno 2.0 results - kit 130361 Elliott.

Here is another that will get the 2.0 results for free - kit 154690 Bunch.
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gtc
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« Reply #69 on: October 07, 2012, 09:01:51 AM »

At least one person has reported being billed for their kit. This may indicate that shipping is about to commence.
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Y-DNA: R1b-Z12* (R1b1a2a1a1a3b2b1a1a1) GGG-GF Ireland (roots reportedly Anglo-Norman)
mtDNA: I3b (FMS) Maternal lines Irish
Richard Rocca
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« Reply #70 on: October 07, 2012, 02:00:26 PM »

At least one person has reported being billed for their kit. This may indicate that shipping is about to commence.

My cc was charged yesterday as well.
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Maternal: H
wing_genealogist
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« Reply #71 on: October 07, 2012, 02:08:31 PM »

I have also noticed today where their "Check Your Results" page:
https://genographic.nationalgeographic.com/results/ is now live and apparently will work. It would be interesting to learn if any of the "freebies" have received their User Name & Password to enter the site.
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Y-DNA - R1b M157.2 (a private/family subclade of Z6/Z352) 111 markers tested

mt-DNA - J1c2g with the following private mutations: 315.1C 522.1A 522.2C C9974T C16256T (FMS tested and submitted to GenBank)

Autosomal - shows as a typical English ancestry. Tested with 23andMe, FTDNA
df.reynolds
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« Reply #72 on: October 07, 2012, 04:24:55 PM »

I have also noticed today where their "Check Your Results" page:
https://genographic.nationalgeographic.com/results/ is now live and apparently will work. It would be interesting to learn if any of the "freebies" have received their User Name & Password to enter the site.

I haven't.
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seferhabahir
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« Reply #73 on: October 10, 2012, 12:47:20 AM »

I have also noticed today where their "Check Your Results" page:
https://genographic.nationalgeographic.com/results/ is now live and apparently will work. It would be interesting to learn if any of the "freebies" have received their User Name & Password to enter the site.

I haven't.

I haven't either.
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mtDNA: J1c7a

Solothurn
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« Reply #74 on: October 10, 2012, 06:05:42 AM »

Does anybody know if a U152* received a free kit?

Thanks
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H1c3b
ysearch JSN4E
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